Mitochondrial diseases are severe disorders caused by genetic mutations that impair energy production, leading to neurological, muscular, and metabolic dysfunction. With no disease-modifying treatments, research focuses on personalized therapies. Patient-derived organoid models offer a promising platform for drug discovery and precision medicine.
We are dedicated to advancing mitochondrial disease research and drug discovery through cutting-edge 3D organoid models and precision medicine approaches.
We generate high-fidelity patient-derived organoid models to study mitochondrial dysfunction, enabling disease insights and therapeutic discovery.
Using high-throughput screening platforms, we test and validate mitochondrial-targeting therapeutics to restore cellular function.
We develop 3D brain organoids for precision medicine, offering a physiologically relevant platform for drug and treatment validation.
Patient-derived neurons in monolayer cultures provide a simplified platform for high-throughput drug screening and mitochondrial function analysis.
Self-organized brain structures mimicking cortical development and neurodegeneration, providing a platform for disease modeling and therapy testing.
Patient-specific models replicating dopaminergic neuronal networks, ideal for studying mitochondrial dysfunction in neurodegenerative diseases.
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